Wales Dental Research Recognised as World Class
19 July 2019
A clinical trial carried out by the Community Dental Service in Cardiff and Vale University Health Board, in collaboration with the Dental Public Health Unit and the Centre for Trials Research, Cardiff University, has received a prestigious award from the International Association for Dental Research (IADR).
The work which compared the relative clinical effectiveness of commonly available preventive dental interventions received the William J. Gies Award in Clinical Research at the recent IADR scientific meeting in Vancouver, Canada. The prize is awarded to the best clinical paper published in the Journal of Dental Research, the most highly ranked dental journal in the world.
Professor Ivor Chestnutt, who led the research and received the award on behalf of the study team commented:
“This award demonstrates that we have the capacity in Wales to conduct impactful research that has implications for dental prevention, not only locally, but across the world. This work was facilitated by close collaboration between the NHS and Cardiff University and is just recognition of the tremendous efforts of a large team of clinical and research staff, in seeing the work to completion. Assistance from Health and Care Research Wales in relation to funding and governance aspects of the work was also key to successful delivery.”
The research was funded by the National Institute for Health Research and Health and Care Research Wales and formed an element of the oral and dental workstream of the Health Research and Health and Care Research Wales funded Primary and Emergency Care (PRIME) Centre Wales.
Pictured is Professor Chestnutt (third left) receiving the award from Professor Rena D'Souza, President of the International Association for Dental Research, Prof William Giannobile, Editor of the Journal of Dental Research, and Professor Maria E. Ryan, President of the American Association for Dental Research.
Health and Care Research Wales specialty leads
19 July 2019
Health and Care Research Wales is recruiting specialty leads and applications are invited in the following specialty areas (commencing as soon as possible until end March 2022):
- Dementias and Neurodegeneration
- Ear, Nose and Throat
- Health Services Research
- Public Health
Health and Care Research Wales sponsors award to recognise outstanding research delivery
19 July 2019
Health and Care Research Wales is proud to be one of the key sponsors of the 2019 Advancing Healthcare Awards Wales. Read more and enter the awards.
Finger-prick blood test at GP surgery could safely reduce antibiotic use in patients with chronic obstructive pulmonary disease
11 July 2019
A simple finger-prick blood test could help prevent unnecessary prescribing of antibiotics for people with the lung condition chronic obstructive pulmonary disease (COPD), according to a new study published in the New England Journal of Medicine by researchers from PRIME Centre Wales, Cardiff University, University of Oxford and King’s College London.
With funding from the National Institute for Health Research, the team demonstrated that using a CRP finger-prick blood test resulted in 20% fewer people using antibiotics for COPD flare-ups. Importantly, this reduction in antibiotic use did not have a negative effect on patients’ recovery over the first two weeks after their consultation at their GP surgery, or on their well-being or use of health care services over the following six months.
Safely reducing the use of antibiotics in this way may help in the battle against antibiotic resistance.
ABACus 3 study update: Trial recruitment, retention, and a little bit more!
6th July 2019
We are firmly in the final year of the ABACus 3 trial funding and are pleased to report that recruitment is completed, follow-up is nearly finished and the task of analysis is underway.
ABACus 3 is a randomised controlled trial of a health check intervention to improve cancer symptom awareness and help-seeking among people living in socioeconomically deprived communities across South Wales and Yorkshire.
The Health Experiences of Asylum seekers and Refugees (HEAR) study Stakeholder Event
Dr Ashra Khanom, Health and Care Research Wales Research Fellow at PRIME, Swansea University and lead researcher on the HEAR study, co-hosted the HEAR stakeholder event with Public Health Wales on the 22nd May 2019. Healthcare professionals and third sector stakeholders gathered for a presentation of the results of the HEAR study and took part in an interactive workshop to discuss future steps towards implementing its recommendations.
Asylum nurses, midwives, GPs and GP receptionists, and people seeking sanctuary joined representatives from the British Red Cross, Welsh Refugee Council and Displaced People in Action to make up an audience of about 50 people from across Wales. The report has been made available in English, Welsh and Arabic.
Fully funded KESS 2 MSC Scholarship
Comparing the value of community based and hospital eye service provision of referral refinement
*This scholarships is part funded by the Welsh Government’s European Social Fund (ESF) convergence programme for West Wales and the Valleys.*
Wet age-related macular degeneration (wet AMD) is common and causes severe sight loss and blindness. A confirmed diagnosis is required before invasive active disease is treated until it becomes inactive; patients are then monitored regularly in hospital in case the disease reactivates, at which point further treatment is needed. A diagnosis of “suspected” wet AMD made in primary care requires confirmation by an ophthalmologist. If a preliminary diagnosis wet AMD is made, this can cause patients’ considerable concern and if the diagnosis is not confirmed at a Hospital Eye Services (HES) appointment, the worry has been unnecessary and a scarcer HES resource has been consumed that might be more productively utilised by another patient. A referral refinement service should reduce the number of unnecessary referrals into the HES reducing stress for patients and demand for out-patient appointments.
Monitoring is also burdensome to patients, their carers and the HES. Provision of a follow-up service in the community may have considerable benefits to both patients by being local and more flexible and taking the pressure away from the HES.
Lead supervisor: Dr Pippa Anderson, Swansea University
Deadline for applications: 19 July 2019
Study start date: October 2019
Health and Care Research Wales conference 2019 - Call for abstracts for presentations and posters
We are pleased to announce that submissions are now open to present at a showcase session or display a poster at the Health and Care Research Wales conference on 3 October at Sophia Gardens, Cardiff. Read more and submit.
Public Involvement Achievement award 2019
Entries are now invited for the 2019 Health and Care Research Wales Public Involvement Achievement award.
The recently launched UK Standards for Public Involvement in Research provide the foundation for the 2019 award. The award is designed to identify, promote, and celebrate the excellent public involvement taking place across the Health and Care Research Wales infrastructure.
PRIME Associate Director appointed to Marie Curie Research Funding Committee
Congratulations to Clare Wilkinson, Professor of General Practice at Bangor University and Associate Director of PRIME Centre Wales who has been appointed to serve on the Marie Curie Research Funding Committee.
Professor Wilkinson says:
"I am delighted to be able to serve on this Committee, chaired by my colleague Professor Tim Peters Bristol University, who asked me to bring randomised trials expertise to the area of end of life care research."
We want to define a better future for cancer patients in Wales and beyond.
As a nation, Wales produces some of the world’s leading cancer research. We want your thoughts to help shape a strategy that is being developed to strengthen the work that happens here.
This is your strategy. Help us make it the best it can be.
Join us at one of our consultation events:
- 7 August – Wrexham, Catrin Finch Centre, Glyndwr University, 13:30 – 15:30
- 15 August – Newport, Barnabas Arts Centre, 13:00 – 15:00
- 10 September – Aberystwyth, Arad Goch Theatre, 13:00 – 15:00
Further information: www.walescancerresearchcentre.org/strategy-consultation/
Registration for consultation events: https://www.eventbrite.co.uk/e/cancer-research-strategy-for-wales-consultation-tickets-64166583980
Read the latest issue of @ResearchWales
24 June 2019
Issue 6 of the @ResearchWales magazine is out now.
Read about PRIME Centre Wales' research collaboration with Cwm Taf Morgannwg UHB and Cardiff University School of Optometry and Vision Sciences aimed at improving urgent eye care on page 11.
KESS2 East PhD in Public Health: Evaluation of errors in the delivery of care to patients with eye-related problems
This PhD scholarship represents an opportunity to train to become a Public Health academic.
The outcome of this collaborative project on eye-related patient safety will be to investigate and identify priority patient safety challenges in eye care and inform recommendations for improvements in services and patient safety reporting by optometrists. The student will also gain the practical experience of working in partnership with the professional body, Optometry Wales.
Supervisors: Dr Jennifer Acton, Dr Andrew Carson-Stevens & Prof Rachel North
Application deadline: 8 July
31 May 2019
PRIME Research Fellow, Dr Rhiannon Phillips has written a guest blog on our work around pregnancy and long-term conditions for the WRISK project. The WRISK project is a collaboration between the British Pregnancy Advisory Service (bpas) and Heather Trickey at the School of Social Sciences at Cardiff University. Working with stakeholders from a wide range of disciplines, the project draws on women’s experiences to understand and improve the development and communication of risk messages in pregnancy.
Health and Care Research Wales Senior Research Leaders Announced
02 April 2019
Congratulations to Adrian Edwards (PRIME Centre Wales Director and Professor of General Practice, Cardiff University), Helen Snooks (PRIME Associate Director and Professor of Health Services Research, Swansea University) and Kerry Hood (PRIME Executive Committee member and Professor of Trials, Cardiff University) who have all been selected to be part of the new group of Health and Care Research Wales senior research leaders.
Individuals have been appointed following a competitive process and assessment by an independent panel of senior UK health and social care experts.
Professor Snooks comments:
"I am delighted to receive this award which reflects the achievements of my team in the Swansea based section of PRIME, focussing on prehospital emergency and primary care, their interfaces and particularly the care of vulnerable groups.
The award will allow us to further invest in capacity building for research both in the academic and NHS settings, as well as ensuring opportunities for dissemination are used to maximise impact in the real world of policy and practice."
Health and Care Research Wales senior research leaders will act as ambassadors for Health and Care Research Wales and play a leading role in raising the profile of health and social care research in Wales on a national and international level.
Sanctuary seekers and health professionals in Wales call for accessible health and wellbeing services for all
02 April 2019
Findings from the 'Health Experiences of Asylum Seekers and Refugees in Wales (HEAR)' study led by PRIME researchers at Swansea University have been published in a new Public Heath Wales report.
The study found that people seeking sanctuary, including refugees and asylum seekers, are struggling to access health and wellbeing services in Wales.
People seeking sanctuary reported feeling their needs were not recognised, and that they had experienced problems navigating through services, including language difficulties and a lack of appropriate interpretation.
Some respondents said the stress of being an asylum seeker or refugee contributed to their poor physical and mental health.
In a survey conducted as part of the HEAR study, nearly a quarter (23 per cent) of respondents said they did not know how to contact, or had not heard of, the 999 ambulance service.
PRIME Associate Director shortlisted in inaugural Welsh Women's Awards
01 April 2019
Congratulations to Clare Wilkinson, Professor of General Practice at Bangor University and Associate Director at PRIME Centre Wales, who has been shortlisted in the inaugural Welsh Women's Awards 2019.
Prof Wilkinson leads the North Wales Centre for Primary Care Research at Bangor University and conducts research into improving primary care and early cancer diagnosis for people in Wales.
Professor Wilkinson comments:
“I am honoured to be nominated among such outstanding women in Wales, it is a delight to see all the categories and the women who populate them".
Making decisions about research: How can we support families?
28 March 2019
Victoria Shepherd, NIHR Doctoral Research Fellow at PRIME and CTR, Cardiff University recently hosted an event 'Making decisions about research for others - how can we support families?' held 25th March.
As part of her PhD, Victoria has been developing a decision-support tool to support making decisions about research for others with impaired capacity.
The aim of the event was to bring together family members, carers, researchers, research nurses and others with an interest in helping families make decision and ask them to consider the tool, and offer feedback before it is finalised.
Following the day, Victoria has produced a report from the event which summarises the discussion, available online at: https://my.visme.co/projects/1jov6ewm-making-decisions-about-research
Can Machine Learning hold the key to making the most from patient safety incident reports?
10 March 2019
Improving patient safety…. the answers are in the data, but the challenge in the sheer quantity of data to analyse.
Learning from patient safety incident reports is a vital part of improving healthcare. However, the volume of reports and their largely free-text nature poses a major analytic challenge.
A recent study led by the Patient Safety team at PRIME Centre Wales, Cardiff University, has found that supervised machine learning can be used effectively to classify patient safety incident report categories.
4 March 2019
Health Technology Wales (HTW), an independent and innovative national body, has opened a Topic Call on St David’s Day.People are being encouraged to suggest non-medicine technologies that could improve health and social care in Wales.
From clinical commissioners and frontline care providers, to patients and members of the public, anyone can suggest a topic on Health Technology Wales’ website.
“Health Technology Wales will provide independent, evidence-informed Guidance on the clinical and cost effectiveness of non-medicine technologies to provide assistance to the Welsh care sector in its health technology adoption decisions,” said Dr Peter Groves, Chair of Health Technology Wales.
Non-medicine technologies can include; devices and diagnostic tests, implants, surgical procedures, psychological therapies and changes in treatment pathways. Topic referrals can also reflect the priority areas of the Welsh Government.
Health Technology Wales is currently planning its 2019 work programme to support a strategic, national approach to the identification, appraisal and adoption of non-medicine health technologies into Welsh health and social care settings.
Speciality Leads Awards 2019
25 February 2019
PRIME Centre Wales staff will continue to have ongoing involvement with the Health and Care Research Wales Speciality Leads following the recently completed recruitment process for 2019-21.
Congratulations to PRIME colleagues:
- Mr Nigel Rees (PRIME stakeholder lead for Welsh Ambulance Services Trust) and Dr Ceri Battle who have been announced as the new Speciality Leads for injuries and emergencies (taking over from Professor Helen Snooks, PRIME Associate Director)
- Dr Andrew Carson-Stevens (PRIME lead for Patient Safety) announced as Speciality Lead for Primary Care, taking over from PRIME Director Adrian Edwards
- Professor Ivor Chestnutt (PRIME lead for Oral and primary dental care) who continues in the role as Speciality Lead for Oral and dental heath.
Specialty Leads in Wales provide important strategic support as part of the Health and Care Research Wales Support & Delivery Service, building networks of principal investigators within their specialty and supporting the uptake of studies throughout Wales.
They map onto the 30 National Institute for Health Research (NIHR) therapeutic areas and provide strong UK-level engagement for Wales.
The full list of new leads can be viewed at: https://www.healthandcareresearch.gov.wales/news/health-and-care-research-wales-specialty-leads-2019/
Award at Cancer Research UK Early Diagnosis Research Conference
22 February 2019
The WICKED research team, based at Bangor University, won the prize for the best scientific poster at the CRUK Early Diagnosis Conference in Birmingham 12th to 13th February.
The poster entitled "Development of a primary care behaviour change intervention to expedite the diagnosis of symptomatic cancer in Wales a multi-dimensional approach" presented by Stefanie Disbeschl, illustrated an overview of the work on the research programme to date.
On behalf of the team, co-leaders Clare Wilkinson and Richard Neal, said:
'This is a terrific prize for the team to win, and a reflection of the quality of the research programmes to date, and the upcoming primary care feasibility trial.
Our goal is to improve cancer diagnosis through primary care in Wales. We are indebted to Cancer Research Wales for their funding, and for the support of PRIME Centre Wales'.
Read more about the WICKED study here.
The research team pictured opposite (left to right): Rebecca-Jane Law, Stefanie Disbeschl, Julia Hiscock, Ruth Lewis and Maggie Hendry).
The Welsh Institute for Health and Social Care (WIHSC) are seeking to appoint an enthusiastic and committed candidate to the post of Senior Research Fellow. The post-holder in this important position will make substantial contributions to research, publication and income generation aligned to the research and evaluation activities of WIHSC and the School of Care Sciences.
The post-holder will be expected to contribute to the University’s REF submission and have a track record of income generation and publications, having completed their PhD in a relevant area in recent years. They will possess a breadth and depth of specialist knowledge in the field of health and social care policy, commissioning and provision across the statutory, independent and third sectors within Wales and the UK.
Further information: https://jobs.southwales.ac.uk/en/vacancies/6166/senior_research_fellow/#job-advert
KESS2 East PhD in Medicine:
Understanding the relationship between HIV pre-exposure prophylaxis, sexually transmitted infections, and antimicrobial resistance in Wales (UNREST)
Working in partnership with Cardiff University, Public Health Wales, and Terrence Higgins Trust Cymru; this mixed methods KESS2 East PhD studentship will aim to understand the relationship between PrEP, STIs, and antimicrobial resistance in Wales.
The PhD will involve: i.) Literature reviewing and critical appraisal of current evidence; ii.) Epidemiological research methods using routinely collected data; iii.) Qualitative interviews with individuals accessing PrEP through sexual health clinics; iv.) Causal modelling methods.
The student will join a research team that crosses the disciplines of public health, statistics, sociology, and systematic reviews. Research students are all members of Cardiff University’s Graduate College, which exists to foster an intellectually stimulating environment where students are encouraged to share and develop research interests with peers from other Schools and to feel part of a wider cross-disciplinary research community.
The student will also spend time at the partnership organisations gaining considerable experience of HIV and sexual health from both public health policy and advocacy perspectives.
Application dedaline: 15 April 2019
Further information: https://www.cardiff.ac.uk/study/postgraduate/funding/view/kess2-east-phd-in-medicine-understanding-the-relationship-between-hiv-pre-exposure-prophylaxis,-sexually-transmitted-infections,-and-antimicrobial-resistance-in-wales-unrest
Preparedness of primary dental care for the phase-down of dental amalgams
Dental amalgam has been the primary material for the restoration of cavities resulting from dental decay for well over a century. The material is durable, safe, easy to use and has been the bedrock of tooth restorations in dental practice for many generations.
However, increasing concerns over the effects of mercury on the environment, (mercury release from crematoria being a particular concern), has seen legislation being enacted by the European Union to phase out the use of dental amalgam.
The study reported in the British Dental Journal describes the state of preparedness of general dental practitioners in Wales in relation to these changes and their perception of the use of alternative plastic (white) filling materials. The study was funded by PRIME’s predecessor body, the Wales School for Primary Care Research.
Lynch, C.D., Farnell J.J., Stanton, H., Chestnutt I.G., Brunton, P.A. and Wilson, N.H.F. (2018) No more amalgams: Use of amalgam and amalgam alternative materials in primary dental care. British Dental Journal, 225, 171-176. DOI: 10.1038/sj.bdj.2018.538
2020 Year of the Nurse Celebrating Nursing and Midwifery endorsed by WHO Executive Board
31 January 2019
The International Council of Nurses (ICN) and the Nursing Now campaign are delighted to support the endorsement by the World Health Organization Executive Board (WHO EB) to designate 2020 as the Year of the Nurse and Midwife. The recommendation was made yesterday evening in Geneva by Dr Tedros Adhanom Ghebreyesus, Director-General of WHO. The proposal will go to the World Health Assembly in May for its consideration.
Noting that 2020 will be the 200th anniversary of the birth of Florence Nightingale, and recognising her contribution to health and humanity, Dr Tedros said that, “Nurses and midwives play such a vital role in delivering Health for All”. Click here to watch Dr Tedros’ speech. Read more
Improvements needed to out of hours palliative care
29 January 2019
A better understanding of risks and causes of harm for out of hours palliative care is urgently needed to ensure patient safety, a study conducted by the patient safety team at PRIME and funded by terminal illness charity Marie Curie and the RCGP has found.
Out of hours care refers to care needed by anyone – not only those with palliative care needs - between 6.30pm and 8am Monday to Friday, on weekends and during bank holidays. Out of hours palliative care is for people with a terminal illness who have end of life care and support needs.
With General Practice looking after an ageing population with increasingly complex care needs, it is vital to have good palliative care support for patients and their families, out of hours in people’s homes.
Making decisions about research for others - how can we support families?
28 January 2019
Following on from the DECISION Study, a decision support intervention is being developed to help family members make a decision about research participation on behalf of someone who lacks capacity to consent. We are holding an event to discuss the prototype tool and gather feedback in order to further refine it.
It is a half day event on the morning of Monday 25th March in Cardiff, and we are inviting those with experience as researchers in this area, and those with lived expertise as families of someone living with dementia, to join us.
If you have been involved in research with adults who lack capacity to consent, or are a family member of someone living with dementia, please contact Vicky Shepherd (ShepherdVL1@cardiff.ac.uk ) for more details or to register an interest in joining the event.
What works to support the mental health of young people leaving statutory social care in Wales?
The Wales Doctoral Training Partnership, the Economic and Social Research Council (ESRC), and Welsh Government are offering a fully funded PhD opportunity.
The successful candidate will evaluate what works to support the mental health of young people leaving statutory care. We anticipate that you will use a mixed methods realist approach to co-produce theory with care leavers, social workers and policy-makers to explore what it is that works to support care leaver mental health.
You will conduct a rapid realist systematic review and case studies of models of transition in Wales. Case studies will involve interviews with care leavers, social workers and other relevant practitioners, and policy-makers.
The collaborator, Health and Care Research Wales, will provide you with direct access to relevant policy-makers in Welsh Government. This close relationship between research and policy is a unique opportunity to ensure that your research has both relevance to and impact on social care practice.
Applications are sought from candidates with backgrounds in social science (especially psychology, health services research, social care research). Experience or interest in realist approaches and both qualitative and quantitative research is desirable.
Deadline for applications: 1 February 2019
Call for applications – Let’s celebrate your achievements!
Nominations are now open for the Research Impact Awards 2019.
Let’s showcase the hard-working, high-achieving staff from the Support and Delivery service that have made a difference to research and development in Wales.
But we can only honour these research stars with your help.
SAPC 2019 call for abstracts is open - deadline 17th February
Primary Care: Arriving? Or departing?
The annual conference will showcase the latest research and education in academic primary care from the UK and around the world in keynote presentations, parallel sessions of verbal presentations, posters, workshops and symposia. The programme will also feature lightning presentations (short 5 minute slots), poster pitches and a creative arts stream.
Visit the call for abstracts page to submit your work: https://mailchi.mp/6bba1465f46d/gjpb1uh63o-3390273?e=a211b2ed2a
PhD Studentship open to applications
This longitudinal, cross-Wales, multicentre case study will be looking at the 'what, when and how' to teach genomics to (mainstream) health professionals.
A three year, EU funded, PhD studentship available from April 1st 2019 in collaboration with Genomics Partnership Wales. [
This studentship is funded by the EU through the Knowledge Economy Skills Scholarships (KESS). The successful candidate will be looking at learning needs and preferences of NHS staff; approaches to education delivery and measuring changes in knowledge and attitudes.
Wales and other countries are investing heavily to embed genomic healthcare within their health services and so this is a very timely study as staff education has, to date, lagged significantly behind investment in technological infrastructure. I’d encourage anyone with an interest in (health) workforce development and training, (adult) education or behaviour change to apply.
The genomics education for NHS staff (that will occur alongside this PhD) will be delivered through Genomics Partnership Wales and so candidates do not need a background in genomics. We have a supervision team that includes an educationalist and a psychologist (who has worked with previously with the Director of Studies on behaviour change, genomics and the health workforce).
Closing date for applications: 27 January 2019
Further information: Please see link below for further details or contact project supervisor Emma Tonkin: (firstname.lastname@example.org / 01443 483156).
14 December 2018
The fifth issue of the @ResearchWales magazine is now live, featuring the latest health and social care research news from across Wales including PRIME Centre Wales' focused news stories:
- 'The Welsh ‘code-breaker’ making our visits to the GP safer' - looking at how analysis of patient safety incident records is being used to improve patient safety in primary care in Wales and beyond, led by Andrew Carson-Stevens is (pages 16-17).
- 'PRIME & Swansea Centre for Health Economics helping to improve community care services' - looking at the evaluation of the community based pathfinder service for treating Wet Age Related Macular Degeneration (Wet AMD) in the community, led by Rachel North (page 5).
PhD - Engaging high-risk disadvantaged populations in shared decision making about low-dose computed tomography lung cancer screening
Fully funded PhD studentship open to applications
Low-dose computed tomography (LDCT) lung cancer screening has become the standard of care for high-risk groups in the US, and the case for implementation of stratified screening is building in the UK. Despite a 20% reduction in lung cancer mortality (Aberle et al, 2011), LDCT screening is not without harms, and in accordance with healthcare policy in Wales (Bradley et al, 2014; Atherton et al, 2016) patients need to be educated about the potential benefits, harms and limitations of screening so that they make a decision that is right for them. Lung cancer disproportionately affects individuals from disadvantaged communities in Wales, and if LDCT screening is to be introduced, we need to understand how we can best support disadvantaged populations to become involved in shared decision making regarding their lung screening decision in a way that avoids widening socioeconomic inequalities in lung cancer outcomes.
The aim of the proposed PhD is to understand how we can best support shared decision making regarding low-dose computed tomography in high-risk disadvantaged populations in Wales, with a view to developing a patient decision support intervention.
Deadline for applications: 27 February 2019
Further information: https://www.findaphd.com/phds/project/phd-in-population-medicine-engaging-high-risk-disadvantaged-populations-in-shared-decision-making-about-low-dose-computed-tomography-lung-cancer-screening/?p104756
PhD - Adverse childhood experiences and their association with child health and development in low and middle income countries
Fully funded PhD studentship open to applications
Supervisors: Lisa Hurt, Victor Adekanmbi
Adverse childhood experiences (ACEs) are potentially traumatic events that may have lasting effects on health and wellbeing. Exposure to ACEs has been shown to be associated with poor child and adult outcomes in high income countries, but very little is known about their burden or effects in low and middle income countries (LMICs) and whether they are important predictors of child outcomes once socio-economic status has been accounted for.
This PhD project will:
- Examine the burden of ACEs in LMICs;
- Examine whether there is an association between ACEs and child health and development outcomes in LMICs; and
- Examine how ACEs might be understood and used in preventative public health programmes in LMICs.
Deadline for applications: 27 February 2019
Further information: https://www.findaphd.com/phds/project/phd-in-population-medicine-adverse-childhood-experiences-and-their-association-with-child-health-and-development-in-low-and-middle-income-countries/?p104748
PhD - Antimicrobial stewardship for asthma exacerbation
Fully funded PhD studentship open to applications
Division of Population Medicine, Cardiff University
Supervisors: Dr Nick Francis, Prof Shantini Paranjothy
This project addresses the priority area antimicrobial resistance (AMR), which is a key public health threat. Use of antibiotics drives AMR and most antibiotics are prescribed in primary care. Previous research and antimicrobial stewardship activities have addressed overuse of antibiotics for many conditions, but antibiotic use of asthma exacerbations is under-researched. More than one in ten people have a diagnosis of asthma at some point.
Most asthma exacerbations are not caused by bacterial infections, systematic reviews of poor quality studies have not found convincing evidence of benefit from antibiotic treatment, and guidelines recommend against antibiotic treatment, but around half of GP consultations for asthma exacerbations are treated with antibiotics.
This project aims to better describe the use of antibiotics for asthma exacerbations (including children who are prescribed asthma medications but do not have a diagnosis of asthma), determine the effect of antibiotics on reducing serious outcomes such as pneumonia and hospital admissions in people with asthma exacerbations, and understand the factors leading to antibiotic prescribing for asthma exacerbations in primary care.
Deadline for applications: 27 February 2019