Investigating the prodrome of Type 1 diabetes in childhood using SAIL and Brecon Group data to reduce ketoacidosis at presentation 

Principal / Lead investigator
Co-investigators / research team
Type of study

Cohort data linkage study


The aim of the research is to get a better understanding of the pathway to diagnosis of Type 1 diabetes (T1D) in childhood. By exploring the number, reason and any point of care tests conducted at children’s appointments with their GP, prior to being diagnosed with T1D, we may be able to develop interventions to aid earlier diagnosis. Earlier diagnosis is critical to ensure children do not present seriously unwell or die with diabetic ketoacidosis (DKA) at diagnosis.

Who is the study sponsor?

Cardiff University


The Novo Nordisk UK Research Foundation

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Amount accruing to your group (if different)


Start date


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How could this research potentially benefit patients?

This study will inform further development of the GP and GP practice nurse intervention with the aim to reduce mortality and morbidity of patients with potential cost benefits to the health service.

Further information (e.g. related web link)


Outputs generated (Reports / Publications / Impact)

To follow